Clinical depression is a recurrent illness requiring treatment and often hospitalization. Nearly 50% of people who have an episode of major depression will have a recurrence within 2-3 years. Being able to prevent the recurrence of depression in people who are at risk for the disease would go a long way to alleviate the pain and suffering of patients.
During the 1980’s the federal government, through the National Institutes of Health (NIH), sponsored a large clinical trial to evaluate two drugs for depression. There were 3 treatment groups. Patients received either Imipramine (Imip), Lithium (Li), or a Placebo (Pl). Researchers randomly assigned patients to one of the 3 treatment groups and followed them for 2-4 years to track any recurrences of depression.
(Prien et al., Archives of General Psychiatry, 1984).
Summary statistics for AcuteT:
Group by: Treat
|Treat||n||Mean||Variance||Std. dev.||Std. err.||Median||Range||Min||Max||Q1||Q3|
- Hospt: Which hospital the patient was from: Labeled 1, 2, 3, 5 or 6
- Treat: 0=Lithium; 1=Imipramine; 2=Placebo
- Outcome: 0=Success 1=Failure (recurrence of depression)
- Time: Number of weeks until a recurrence (if outcome=1) or until study ended (if outcome=0)
- AcuteT: How long the patient was depressed before the start of the current study, measured in days
- Age: Age in years
- Gender: 1=Female 2=Male
example for soultion at the word file